diff --git a/configure b/configure
index d22c0cf89cc..e1699b7e765 100755
--- a/configure
+++ b/configure
@@ -5868,7 +5868,6 @@ if test "x$enable_win64" = "xyes"
 then
     test -z "$with_wine64" || as_fn_error $? "--enable-win64 and --with-wine64 are mutually exclusive.
 --enable-win64 should be used in the 64-bit build tree, --with-wine64 in the 32-bit Wow64 build tree." "$LINENO" 5
-    test "x$libdir" != "x\${exec_prefix}/lib" || libdir="\${exec_prefix}/lib64"
 fi
 
 case $host_cpu in
diff --git a/configure.ac b/configure.ac
index c90e78d8bb7..ebe9497522c 100644
--- a/configure.ac
+++ b/configure.ac
@@ -235,7 +235,6 @@ if test "x$enable_win64" = "xyes"
 then
     test -z "$with_wine64" || AC_MSG_ERROR([--enable-win64 and --with-wine64 are mutually exclusive.
 --enable-win64 should be used in the 64-bit build tree, --with-wine64 in the 32-bit Wow64 build tree.])
-    test "x$libdir" != "x\${exec_prefix}/lib" || libdir="\${exec_prefix}/lib64"
 fi
 
 dnl Normalize CPU architecture
diff --git a/dlls/ntdll/unix/loader.c b/dlls/ntdll/unix/loader.c
index a575fb21b76..e4c062cea98 100644
--- a/dlls/ntdll/unix/loader.c
+++ b/dlls/ntdll/unix/loader.c
@@ -977,7 +977,7 @@ static void load_libwine(void)
     void *handle;
 
     if (build_dir) path = build_path( build_dir, "libs/wine/" LIBWINE );
-    else path = build_path( dll_dir, "../" LIBWINE );
+    else path = build_path( ntdll_dir, LIBWINE );
 
     handle = dlopen( path, RTLD_NOW );
     free( path );
diff --git a/tools/makedep.c b/tools/makedep.c
index 638af2b6a44..f19ddfc6b74 100644
--- a/tools/makedep.c
+++ b/tools/makedep.c
@@ -3525,14 +3525,12 @@ static void output_shared_lib( struct makefile *make )
     output_filenames( all_libs );
     output_filename( "$(LDFLAGS)" );
     output( "\n" );
-    add_install_rule( make, make->sharedlib, make->sharedlib,
-                      strmake( "p$(libdir)/%s", make->sharedlib ));
+    add_install_rule( make, make->sharedlib, make->sharedlib, strmake( "p%s/%s", so_dir, make->sharedlib ));
     for (i = 1; i < names.count; i++)
     {
         output( "%s: %s\n", obj_dir_path( make, names.str[i] ), obj_dir_path( make, names.str[i-1] ));
         output_symlink_rule( names.str[i-1], obj_dir_path( make, names.str[i] ), 0 );
-        add_install_rule( make, names.str[i], names.str[i-1],
-                          strmake( "y$(libdir)/%s", names.str[i] ));
+        add_install_rule( make, names.str[i], names.str[i-1], strmake( "y%s/%s", so_dir, names.str[i] ));
     }
     strarray_addall( &make->all_targets, names );
 }