diff --git a/Make.rules.in b/Make.rules.in
index 130abbd3407..fd7166f4939 100644
--- a/Make.rules.in
+++ b/Make.rules.in
@@ -14,6 +14,7 @@
 # First some useful definitions
 
 INCLUDES     = -I$(srcdir) -I. -I$(top_srcdir)/include -I$(top_builddir)/include $(EXTRAINCL)
+DEFS         = -D__WINESRC__ $(EXTRADEFS)
 ALLCFLAGS    = $(INCLUDES) $(DEFS) $(DLLFLAGS) $(EXTRACFLAGS) $(CPPFLAGS) $(CFLAGS) $(MODCFLAGS)
 ALLLINTFLAGS = $(INCLUDES) $(DEFS) $(LINTFLAGS)
 IDLFLAGS     = $(INCLUDES) $(DEFS) $(EXTRAIDLFLAGS)
diff --git a/Maketest.rules.in b/Maketest.rules.in
index 56174d8fba7..7ba3060d2d6 100644
--- a/Maketest.rules.in
+++ b/Maketest.rules.in
@@ -9,8 +9,6 @@
 #
 
 DLLFLAGS     = @DLLFLAGS@
-DEFS         = -D__WINESRC__ $(EXTRADEFS)
-
 MODULE       = $(TESTDLL:%.dll=%)_test.exe
 TESTRESULTS  = $(C_SRCS:.c=.ok)
 TESTPROGRAM  = $(MODULE)$(DLLEXT)
diff --git a/dlls/Makedll.rules.in b/dlls/Makedll.rules.in
index b34a35a0297..dba64f6c887 100644
--- a/dlls/Makedll.rules.in
+++ b/dlls/Makedll.rules.in
@@ -8,7 +8,6 @@
 #
 
 DLLFLAGS    = @DLLFLAGS@
-DEFS        = -D__WINESRC__ $(EXTRADEFS)
 BASEMODULE  = $(MODULE:%.dll=%)
 MAINSPEC    = $(BASEMODULE).spec
 ALL_LIBS    = $(LIBPORT) $(EXTRALIBS) $(LDFLAGS) $(LIBS)
diff --git a/dlls/Makeimplib.rules.in b/dlls/Makeimplib.rules.in
index 0a22784f3ec..51129485e06 100644
--- a/dlls/Makeimplib.rules.in
+++ b/dlls/Makeimplib.rules.in
@@ -7,7 +7,6 @@
 #
 
 DLLFLAGS = @DLLFLAGS@
-DEFS     = -D__WINESRC__ $(EXTRADEFS)
 MAKEDEPFLAGS = -xo -xcross.o
 
 @MAKE_RULES@
diff --git a/libs/port/Makefile.in b/libs/port/Makefile.in
index 79bd1fe9e08..3f42fd44165 100644
--- a/libs/port/Makefile.in
+++ b/libs/port/Makefile.in
@@ -1,4 +1,3 @@
-DEFS      = -D__WINESRC__
 DLLFLAGS  = @DLLFLAGS@
 MODULE    = libwine_port.a
 
diff --git a/libs/wine/Makefile.in b/libs/wine/Makefile.in
index be5351e3030..ad9c3c94e7f 100644
--- a/libs/wine/Makefile.in
+++ b/libs/wine/Makefile.in
@@ -1,6 +1,6 @@
 DLLFLAGS  = @DLLFLAGS@
 EXTRALIBS = $(LIBPORT) @LIBDL@ @COREFOUNDATIONLIB@ @CORESERVICESLIB@
-DEFS      = -D__WINESRC__ -DWINE_UNICODE_API=""
+EXTRADEFS = -DWINE_UNICODE_API=""
 
 VERSION   = 1.0
 SOVERSION = 1
diff --git a/loader/Makefile.in b/loader/Makefile.in
index a7859b28a85..9b0436aff14 100644
--- a/loader/Makefile.in
+++ b/loader/Makefile.in
@@ -1,4 +1,3 @@
-DEFS      = -D__WINESRC__ $(EXTRADEFS)
 MODCFLAGS = @BUILTINFLAG@
 
 C_SRCS = \
diff --git a/programs/Makeprog.rules.in b/programs/Makeprog.rules.in
index 9c2cb4b6143..f72ad2e1dba 100644
--- a/programs/Makeprog.rules.in
+++ b/programs/Makeprog.rules.in
@@ -10,7 +10,6 @@
 #
 
 DLLFLAGS    = @DLLFLAGS@
-DEFS        = -D__WINESRC__ $(EXTRADEFS)
 ALL_LIBS    = $(DELAYIMPORTS:%=-l%) $(IMPORTS:%=-l%) $(EXTRALIBS) -lwine $(LIBPORT) $(LDFLAGS) $(LIBS)
 INSTALLDIRS = $(DESTDIR)$(bindir) $(DESTDIR)$(dlldir) $(DESTDIR)$(fakedlldir) $(DESTDIR)$(mandir)/man$(prog_manext)
 
diff --git a/server/Makefile.in b/server/Makefile.in
index 2e9bba1fa82..38e79bcbdb0 100644
--- a/server/Makefile.in
+++ b/server/Makefile.in
@@ -1,4 +1,3 @@
-DEFS      = -D__WINESRC__
 EXTRALIBS = @LIBPOLL@ @LIBRT@
 
 C_SRCS = \
diff --git a/tools/Makefile.in b/tools/Makefile.in
index 91446d62bd7..02feee90d35 100644
--- a/tools/Makefile.in
+++ b/tools/Makefile.in
@@ -1,4 +1,4 @@
-DEFS      = -D__WINESRC__ -DWINE_UNICODE_API=""
+EXTRADEFS = -DWINE_UNICODE_API=""
 EXTRAINCL = @FREETYPE_CFLAGS@
 FREETYPELIBS = @FREETYPE_LIBS@
 
diff --git a/tools/widl/Makefile.in b/tools/widl/Makefile.in
index 4bbcf1e0c18..f12916d0777 100644
--- a/tools/widl/Makefile.in
+++ b/tools/widl/Makefile.in
@@ -1,5 +1,3 @@
-DEFS      = -D__WINESRC__ $(EXTRADEFS)
-
 PROGRAMS = widl$(EXEEXT)
 MANPAGE  = widl.man
 
diff --git a/tools/winebuild/Makefile.in b/tools/winebuild/Makefile.in
index 96bc4f92cb0..190caf31141 100644
--- a/tools/winebuild/Makefile.in
+++ b/tools/winebuild/Makefile.in
@@ -1,5 +1,3 @@
-DEFS      = -D__WINESRC__ $(EXTRADEFS)
-
 PROGRAMS = winebuild$(EXEEXT)
 MANPAGE  = winebuild.man
 
diff --git a/tools/winedump/Makefile.in b/tools/winedump/Makefile.in
index ce6168283a3..e8a6ba31e25 100644
--- a/tools/winedump/Makefile.in
+++ b/tools/winedump/Makefile.in
@@ -1,5 +1,3 @@
-DEFS      = -D__WINESRC__ $(EXTRADEFS)
-
 PROGRAMS = winedump$(EXEEXT)
 MANPAGE  = winedump.man
 
diff --git a/tools/winegcc/Makefile.in b/tools/winegcc/Makefile.in
index 3e8bfdd9fa1..dce7ae26063 100644
--- a/tools/winegcc/Makefile.in
+++ b/tools/winegcc/Makefile.in
@@ -1,4 +1,4 @@
-DEFS = \
+EXTRADEFS = \
 	-DINCLUDEDIR="\"$(includedir)\"" \
 	-DDLLDIR="\"$(dlldir)\"" \
 	-DLIBDIR="\"$(libdir)\"" \
diff --git a/tools/wmc/Makefile.in b/tools/wmc/Makefile.in
index 324ab5154f8..c302c22a719 100644
--- a/tools/wmc/Makefile.in
+++ b/tools/wmc/Makefile.in
@@ -1,4 +1,4 @@
-DEFS     = -D__WINESRC__ -DWINE_UNICODE_API=""
+EXTRADEFS = -DWINE_UNICODE_API=""
 PROGRAMS = wmc$(EXEEXT)
 MANPAGE  = wmc.man
 ALL_LIBS = @LIBGETTEXTPO@ $(LIBWINE_STATIC) $(LIBPORT)
diff --git a/tools/wrc/Makefile.in b/tools/wrc/Makefile.in
index 2ed045359f7..a017891a418 100644
--- a/tools/wrc/Makefile.in
+++ b/tools/wrc/Makefile.in
@@ -1,4 +1,4 @@
-DEFS     = -D__WINESRC__ -DINCLUDEDIR="\"$(includedir)\"" -DWINE_UNICODE_API=""
+EXTRADEFS = -DINCLUDEDIR="\"$(includedir)\"" -DWINE_UNICODE_API=""
 PROGRAMS = wrc$(EXEEXT)
 MANPAGE  = wrc.man
 ALL_LIBS = @LIBGETTEXTPO@ $(LIBWPP) $(LIBWINE_STATIC) $(LIBPORT)